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Medicine safety

Medications That Cause Tinnitus: Ototoxic Drug List

Quick answer

Medications that cause tinnitus include some pain relievers, antibiotics, cancer medicines, water pills, malaria medicines and antidepressants. The term for ear-harming drugs is ototoxic. Most people on these drugs never get ringing. Do not stop a prescribed medicine on your own. Ask your prescriber or pharmacist first.

Written by the Quietum Plus label deskUpdated · 4 min read

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Which medications can cause tinnitus?

Many medicines can cause tinnitus, and the group called ototoxic drugs is the best known. Ototoxic means harmful to the ear.

Mayo Clinic lists NSAIDs, some antibiotics, cancer medicines, water pills, malaria medicines and some antidepressants. It adds that higher doses generally make ringing worse (Mayo Clinic, Tinnitus). The NHS also names aspirin (NHS, Tinnitus). Only a prescriber can say if a drug is the cause.

Drug groups linked to ringing in the ears
GroupCommon useNote
NSAIDs and aspirinPain, fever, swellingHigher doses are the usual concern
Some antibioticsInfectionsOnly certain types
Some cancer medicinesChemotherapyAsk the oncology team
Water pillsBlood pressure, swellingAsk which type you take
Malaria medicinesPrevention, treatmentAsk the travel clinic
Some antidepressantsMoodDo not stop suddenly

What should you do if a medicine may be causing your ringing?

Keep taking prescribed medicine and call your prescriber or pharmacist. Stopping a drug on your own can be harmful, and the ringing may have another cause.

Write down when the ringing started and when you began or changed each drug, vitamin or herb. A clear timeline helps the person who prescribed it decide if the drug is a likely cause.

  1. List everything you take

    Include over-the-counter pain relievers, vitamins, herbs and supplements.

  2. Note the dates

    Mark when ringing began and when any dose changed.

  3. Ask before you change anything

    Your prescriber may adjust the dose, switch drugs or say it is not the cause.

Can supplements and herbs cause ringing too?

Yes, some herbal supplements can cause or worsen tinnitus. Natural does not mean harmless.

The NIDCD adds that no vitamin, herb or supplement advertised for tinnitus has been shown to work (NIDCD, Tinnitus). So adding one in hope of relief can add a new unknown. Tell your doctor or pharmacist about every product you use, including those from our supplements and medicines guide.

Do not self-adjust

Never stop a blood pressure, heart, mood or infection medicine because of ringing. Ask your prescriber what to do next.

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What about Quietum Plus and ringing from medicines?

Quietum Plus is a dietary supplement, not a medicine, and it has not been tested for ringing from drugs. It comes in a white bottle of 60 capsules.

The bottle front prints no serving, no amounts and no directions, so follow your bottle's label. Its sales page lists 18 ingredients, and some, such as piperine, ginger and dong quai, can interact with certain drugs. See the side effects page and ask your doctor or pharmacist before use. Show them the bottle.

When ringing is a doctor question, not a supplement question

Sudden hearing loss in one ear (same day), ringing that beats with your pulse, ringing after a head injury, or ringing with dizziness, weakness or a drooping face. Call 911 for sudden weakness or a drooping face. Sources: NIDCD on sudden deafness (NIDCD, Sudden Deafness), the NHS (NHS, Tinnitus), Mayo Clinic (Mayo Clinic, Tinnitus) and the tinnitus guideline (AAO-HNSF Tinnitus Guideline 2014).

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01FAQ

Drug-related ringing questions

Does ototoxic mean the ringing is permanent?

No. Ototoxic only means a drug can harm the ear. Some effects fade after a dose change, while others can last. A prescriber or audiologist can judge which is likely for your drug and check your hearing if you notice changes.

Can aspirin or ibuprofen make my ears ring?

They can, mostly at higher doses. Mayo Clinic lists NSAIDs and the NHS names aspirin. Many people use them with no ringing. If ringing starts after a pain reliever, ask your pharmacist about options instead of just stopping.

Who should I tell about ringing that began after a new drug?

Tell the prescriber who started it, or your pharmacist, as soon as you notice. If you also have sudden hearing loss or dizziness, seek care the same day. An audiologist can test your hearing for a baseline.

02Who wrote this

Written and reviewed by

Written byThe Quietum Plus label deskGoquietumplus, USA Authorized Quietum Plus Retailer

Pages built from the bottle images, the sales page and linked NIH, NIDCD, FDA, FTC and peer-reviewed sources.

Medically reviewed byDr. Nicole Miller, Au.D, AudiologistRole: Medical reviewerReview date: October 19, 2026

Last updated . Read our editorial standards and how we check reviews. This website is run by Goquietumplus, a USA Authorized Quietum Plus Retailer, not by the manufacturer. We earn money when you buy through our order links.

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